Regarding Pre-existing maternal conditions

From the list given below regarding the pre existing maternal conditions choose an option for each description:
A Diabetes
B Hypertension
C Epilepsy
D Vitiligo
E Factor V Leiden deficiency
F HIV
G Asthma
H Smoking
I Crohn’s disease
J Mitral valve stenosis
K Myasthenia gravis
L Glomerulonephritis

1 Reduces intrauterine growth in a dose-dependent manner.
2 Increases risk of venous thromboembolism (VTE) in the puerperium.
3 Increased frequency of episodes during pregnancy.
4 Risk of fetal macrosomia if condition not well controlled.
5 Maternal muscle fatigue in labour.
6 Requires prophylactic antibiotics for instrumental delivery.

Answers:


1 Reduces intrauterine growth in a dose-dependent manner.
H Smoking

2 Increases risk of venous thromboembolism (VTE) in the puerperium.
E Factor V Leiden deficiency

3 Increased frequency of episodes during pregnancy
C Epilepsy

4 Risk of fetal macrosomia if condition not well controlled.
A Diabetes

5 Maternal muscle fatigue in labour.
K Myasthenia gravis

6 Requires prophylactic antibiotics for instrumental delivery.
J Mitral valve stenosis

Discussion:
Many pre-existing maternal conditions have an impact during pregnancy.

Factor V Leiden deficiency increases the risk of venous thromboembolism throughout life and compounds the normal increase in risk in the puerperium.

Women with epilepsy often suffer from increased fit frequency during pregnancy.

Diabetes can lead to a number of perinatal complications, including fetal macrosomia.

Myasthenia gravis can increase the normal maternal muscle fatigue during the course of labour.

Women with congenital heart valve problems should have antibiotic prophylaxis for infection-prone procedures such as instrumental delivery.