Friday, October 14, 2016

Regarding Dysmenorrhea



Which of the following is considered first-line therapy for primary dysmenorrhea?
A) Nonsteroidal anti-inflammatory drugs (NSAIDs)
B) Selective serotonin reuptake inhibitors (SSRIs)
C) Antiestrogens
D) Acupuncture
E) Tricyclic antidepressants

Answer and Discussion

The answer is A. Nonsteroidal anti-inflammatory drugs (NSAIDs)

Primary dysmenorrhea is associated with cramping pain in the lower abdomen occurring just before and/or during menstruation, in the absence of other conditions such as endometriosis. The initial
presentation of primary dysmenorrhea typically occurs in adolescence. The condition is associated with increased production of endometrial prostaglandin, resulting in increased uterine tone and stronger, more frequent uterine contractions. A diagnostic evaluation is unnecessary in women with
typical symptoms and in the absence of risk factors for secondary causes.
Nonsteroidal anti-inflammatory drugs are the most effective treatment, with the addition of oral contraceptive pills (OCPs) when necessary. About 10% of affected women do not respond to these measures. In these cases, it is important to consider secondary causes of dysmenorrhea in affected
women. Acupuncture is also used as an alternative treatment

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