Monday, October 10, 2016

Extra intestinal features of Inflammatory Bowel Disease



Extra intestinal features of Inflammatory Bowel Disease include all of the following EXCEPT:

A) Alopecia.
B) Arthritis.
C) Sclerosing cholangitis.
D) Uveitis.
E) Cholelithiasis.

Answer and Discussion

The correct answer is “A.” Alopecia.

Alopecia is not an extraintestinal manifestation of IBD.

  • Arthritis related to IBD (enteropathic arthritis) is fairly common and usually migratory in nature, involving the large joints.
  • Spondyloarthropathy may also be seen. 
  • Sclerosing cholangitis and autoimmune hepatitis can occur and may be fatal. 
  • Eye disease may include uveitis and episcleritis. 
Importantly, the main treatment of extraintestinal manifestations is to treat the IBD. IBD spondyloarthropathy and pyoderma gangrenosum are important exceptions, as these do not always improve with treatment of the underlying IBD.

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