Which of the following tests has been shown to be a good predictor of preterm birth in women presenting with symptomatic preterm uterine contractions, and thus help guide the pharmacologic management of preterm labor patients?
A) Screening for genitourinary infections
B) Measurement of salivary estriol
C) Cervical length measurement
D) Fetal fibronectin screening
E) Both C and D
Answer and Discussion
The answer is E. Cervical length measurement and Fetal fibronectin screening
A positive fetal fibronectin testing combined with a shortened cervical length in women presenting with symptoms of preterm labor can be a useful predictor of preterm birth. These screening tests have
been shown to have a high sensitivity and high positive predictive value, as well as a high negative predictive value so they are useful in guiding decisions regarding steroid and tocolytic administration in women who have positive results and allow avoidance of these therapies in women with negative results.
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