Which one of the following may be used to monitor patients with colorectal cancer?
A. CA-125
B. Carcinoembryonic antigen
C. Alpha-fetoprotein
D. CA 19-9
E. CA 15-3
Answer:
B. Carcinoembryonic antigen.
Discussion: Carcinoembryonic antigen may be used to monitor for recurrence in patients post-operatively or to assess response to treatment in patients with metastatic disease.
Colorectal cancer screening :
Overview:
most cancers develop from adenomatous polyps. Screening for colorectal cancer has been shown to reduce mortality by 16%
the NHS now has a national screening programme offering screening every 2 years to all men and women aged 60 to 69 years. Patients aged over 70 years may request screening
eligible patients are sent faecal occult blood (FOB) tests through the post
patients with abnormal results are offered a colonoscopy
At colonoscopy, approximately:
5 out of 10 patients will have a normal exam
4 out of 10 patients will be found to have polyps which may be removed due to their premalignant potential
1 out of 10 patients will be found to have cancer
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