Which of the following medications is used in the classic treatment of bipolar disorder?
A) Lithium
B) Sertraline
C) Amitriptyline
D) Phenytoin
E) Alprazolam
Answer:
A) Lithium
Discussion: Lithium is considered a first-line medication for bipolar disorder and has been more widely studied than any other maintenance treatment for bipolar disorder and is consistently supported across multiple randomized trials.
Bipolar disorder is most commonly diagnosed in persons between 18 and 24 years of age, with the mean age of onset for a first manic, hypomanic, or depressive episode at 18. The clinical presentations of this disorder are diverse and include mania, hypomania, and psychosis.
Frequently associated conditions include substance abuse, attentiondeficit/ hyperactivity disorder (ADHD), and anxiety disorders and other mood disorders. Patients with acute mania must be evaluated urgently.
Treatment involves the use of mood stabilizers such as lithium, valproic acid, and carbamazepine.
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