Thursday, November 10, 2016

Essential Tremors



A 60-year-old woman presents with a tremor. Which one of the following features would suggest a diagnosis of essential tremor rather than Parkinson's disease?
A. Difficulty in initiating movement
B. Tremor is worse following alcohol
C. Postural instability
D. Unilateral symptoms
E. Tremor is worse when the arms are outstretched

Answer:
E. Tremor is worse when the arms are outstretched

Discussion: Difficulty in initiating movement (bradykinesia), postural instability and unilateral symptoms (initially) are typical of Parkinson's.
Essential tremor symptoms are usually eased by alcohol.
Essential tremor (previously called benign essential tremor) is an autosomal dominant condition which usually affects both upper limbs

Clinical Features 
 postural tremor: worse if arms outstretched
 improved by alcohol and rest
 most common cause of titubation (head tremor)

Management 
 propranolol is first-line
 primidone is sometimes used

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